What does OTC mean?

Over the counter skincare products are available without a prescription. You can buy them from pharmacies, supermarkets, and online stores. They include cleansers, moisturisers, and serums that contain active ingredients at concentrations available without a prescription.

In the UK, some active ingredients are classified as medicines and require a prescription, while others are available without a prescription. Checking whether a product requires a prescription or is available over the counter can help you understand where to seek appropriate guidance.

Common OTC active ingredients

Several active ingredients widely used in UK skincare are available without a prescription:

How are prescription skincare products different?

Prescription skincare is assessed and supplied by a qualified professional. Suitability depends on the product, medical history, skin concern, pregnancy or breastfeeding status, other medicines and professional assessment.

Where to buy OTC skincare in the UK

OTC skincare is widely available from multiple sources in the UK:

OTC vs prescription: a broad comparison

The table below is a general overview only. Individual situations vary, and this is not medical advice. Whether OTC or prescription skincare is appropriate depends on individual assessment by a qualified professional.

OTC Skincare Prescription Skincare
Availability Available without a consultation, direct to purchase Requires a consultation with a GP or dermatologist
Access Available without an individual prescription Assessed and supplied by a qualified professional
Cost Available at a range of price points NHS prescription charge applies in England unless exempt; private consultations have a fee
Typical context General skincare routines and cosmetic skincare concerns Assessed and supplied by a qualified professional based on individual assessment
Supervision No professional supervision required Prescribed and monitored by a qualified clinician

Things to consider

When comparing OTC skincare and professional advice, a few practical points may be useful.

Allow time to assess tolerance. Many active skincare products need gradual introduction. Skin tolerance varies, and switching products frequently can make it harder to understand how your skin is responding.

SPF and product instructions matter. Some active skincare products may increase sun sensitivity or require careful SPF use. Check product instructions and follow current sun protection guidance.

Consider speaking with a professional if symptoms are persistent or worsening. A GP, pharmacist, dermatologist, or qualified prescriber can assess your situation and discuss what options may be appropriate.

Tell your GP about everything you are using. If you speak with a clinician about your skin, mention all the products you currently use. This helps them assess safely.

If you are pregnant, breastfeeding, trying to conceive, using prescription skincare, taking regular medication, or managing a diagnosed skin condition

Speak with a GP, pharmacist, midwife, dermatologist or qualified prescriber before using active skincare products or prescription skincare.

If symptoms are painful, rapidly worsening, infected-looking, affecting the eyes, causing swelling, scarring, pigmentation changes, widespread rash, severe irritation, or significant distress

Seek advice from a GP, pharmacist, NHS 111, dermatologist or qualified prescriber. If symptoms feel urgent or severe, use appropriate NHS or local urgent care routes.

Not medical advice

This page is an informational overview only. It does not diagnose, assess or recommend any specific approach. Whether prescription skincare is appropriate for your situation is a decision for a GP, pharmacist, dermatologist or qualified prescriber to make following an individual assessment.